the AN E/SEC vs. the Nautilus...hmm, that'd be a tough one...I'd take the AN E/SEC too I think.
Though I'd love to own either.

I'd put Dr. D'Appolito's SEAS Custom Thor T-Lines up with them too, though...in a heartbeat.
And you could buy a Ferrari for the cost a pair of all 3.

I'll say this about B&W...I cannot think of any other speaker company that is so competitive in just about ever price category available. Most companies seem to have real strengths at a certain level of price/performance, B&W just seems to be good at everything IMO.