madarahr... you don't know how smooth your room is until you evaluate it.
"The Master Handbook of Acoustics" will provide a method to predict room modes based on room dimensions, but this procedure is best done in EXCEL (or equivalent) so that you can then reorder the calculated modes in numerical sequence from lowest to highest to determine how smooth, or how uneven, your room is. You want to see a smoothly rising graph with a uniform slope rather than a series of steps with bunched modes. Note that some judgement will be required when that room's volume is joined to another significant volume by a large opening.
Using more than one sub leads to a lot of work both with regard to placement in the room considering modes and also allowing for cancellation effects between or among subs as a result of their distances apart. If you have two sounds of the same magnitude, frequency, and phase combine, they add to a combined sound 3dB louder than the two original sounds. But if those two sounds are 180 degrees apart in phase, they add to ZERO dB. I have done the two-sub exercise in a large room and it was a good bit of calculating. I am not convinced the work was cost effective but it was fun.
Audio tubes heat up about as quick as a standard lightbulb
So 10 to 30 seconds should make everything fine. Some fret about letting tubes warm for minutes or even hours to get the purest sound, but that is like letting your car warm up for 2 hours so that you get the best gas milage & performance....